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. 2020 Apr 16;15(4):e0231376. doi: 10.1371/journal.pone.0231376

Table 4. KEGG pathway analysis of DEGs.

Pathway term FDR Up Count Down Count
MAPK signaling pathway 1.806E-05 38 17
Protein digestion and absorption 1.806E-05 20 7
PI3K-Akt signaling pathway 2.128E-05 47 21
Ras signaling pathway 0.0001668 31 16
Rap1 signaling pathway 0.0002316 30 10
Serotonergic synapse 0.0008405 16 13
Drug metabolism—cytochrome P450 0.0013631 8 13
Thyroid hormone synthesis 0.0015981 11 8
ECM-receptor interaction 0.0020869 15 4
Relaxin signaling pathway 0.0023643 20 7
Focal adhesion 0.0042909 25 9
Aldosterone synthesis and secretion 0.0048675 16 2
Arachidonic acid metabolism 0.0048675 9 10
Melanogenesis 0.0048675 15 6
Regulation of lipolysis in adipocytes 0.0048675 8 6
Signaling pathways regulating pluripotency of stem cells 0.0048675 16 10
TNF signaling pathway 0.0048675 16 6
Glutathione metabolism 0.0071094 4 11
Calcium signaling pathway 0.0080587 22 10
Basal cell carcinoma 0.0085833 11 4