Skip to main content
. 2020 Apr 6;16(4):e1008242. doi: 10.1371/journal.ppat.1008242

Fig 3. CD300lf is required to generate humoral response after oral MNoVCW3 challenge.

Fig 3

Sera was collected from Cd300lf+/- and Cd300lf-/- mice 14 days after challenge with 106 PFU PO MNoVCW3. (A) The maximal protection (1:10 sera dilution) and (B) sera IC50 was measured by in vitro MNoVCW3 neutralization assay in BV2 cells. (C) Cd300lf+/- generated significantly increased anti-MNoV IgG (C) and IgM (D). Data is pooled from two independent experiments. Data was analyzed by Mann-Whitney test. Shown are means ± SEM. NS, not significant; *P<0.05; **P<0.01; ***P<0.001; ****P<0.0001. L.O.D., limit of detection.