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. 2020 Apr 6;16(4):e1008402. doi: 10.1371/journal.ppat.1008402

Fig 2. Effect of IE2F depletion on transcription in the MIE region.

Fig 2

(A and B) Browser views of PRO-Seq results for HFF infected with untagged IE2 (IE2) or F-tagged IE2 (IE2F) HCMV Towne treated with vehicle or dTag (200 nM) from 90–96 h pi. Flavopiridol (1 μM, Flavo) was added for the final 1 h of infection. PRO-Seq reads were aligned to the HCMV Towne genome (GenBank accession number FJ16285.1). Arrows denote direction of transcription. The MIEP enhancer is composed of dissimilar proximal (blue) and distal (beige) segments. The MIEP crs (vertical orange bar) is located immediately upstream of the TSS.