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Axial CT images of the brain from Patient 1 (A–C) and susceptibility-weighted MR images of the brain from patient 2 (D–F). Panel A, (admission) is normal. Panel B (HD 3) shows prominent, bilaterally symmetric thalamic hypodensities. Panel C (HD 5) shows diffuse, severe cerebral edema. Panels D-F (HD 5) demonstrate innumerable microscopic and small hemorrhages involving nearly all brain regions, with a predilection for subcortical white matter and the middle cerebellar peduncles.
