Skip to main content
. Author manuscript; available in PMC: 2020 Apr 16.
Published in final edited form as: Virus Res. 2013 Dec 25;182:5–20. doi: 10.1016/j.virusres.2013.12.017

Fig. 6. The assembly pathway of the core particle.

Fig. 6

(A) Theinvitroassemblyofcoreparticles.VP1,VP4 andVP6 are translated and mixed with ten BTV ssRNA transcripts.VP3 is then added followed by VP7. Note no non-structural proteins are required. (Adapted from Lourenco and Roy, 2011 (B)). The model of VP7 layer assembly. The T trimer sits on the icosahedral three fold axis where strong interactions with the sub-core layer a present. This trimer nucleates the assembly of trimer positions R to P through lateral association, which bind through weaker quasi-equivalent local interactions with the VP3 sub-core. (Adapted from Limn and Roy, 2003).