Fig. 3.

Effects of L. plantarum OLL2712 on IL-10 production in a DC-T cell co-culture.

Spleen CD4⁺ T cells from DO11.10 mice were co-cultured with MLN DCs (a) or PP DCs (b) in the presence of OVA 323-339 residue peptide (10 nM, 100 nM) and heat-killed L. plantarum OLL2712 (1 µg/mL, 10 µg/mL) for 72 hr. The IL-10 protein in the supernatants was measured by ELISA. The plot shows representative data from one experiment. Data are shown as the mean ± SD of cultured wells (n=3). Two independent experiments were performed. Statistical analysis was performed by Dunnett’s test. *p<0.05; **p<0.01. N.D.: not detected.