Table 5.

Associations between 4 clusters with radiographic disc space narrowing in unadjusted, propensity score matched models and matched and adjusted models.

Cluster	Unadjusted Risk Ratio (95% CI)	Matched* Risk Ratio (95% CI)	Matched and Adjusted** Risk Ratio (95% CI)
1 – Lower Biomarker Level Group	referent	referent	referent
2 – Inflammation / Pain / Structure	1.56 (0.64, 3.78)	3.04 (1.22, 7.54)	2.76 (1.09, 7.03)
3 – Inflammation / Structure	1.38 (0.34, 8.68)	2.60 (0.96, 7.04)	2.35 (0.86, 6.41)
4 – Pain	1.58 (0.64, 3.91)	2.91 (1.15, 7.39)	2.97 (1.17, 7.52)

^*Matched for age, sex, knee OA, hip OA

^**Matched for age, sex, knee OA, hip OA and Adjusted for Depressive Symptoms with CES-D score. Bold items are statistically significant