Table 1.
Comparison of demographics and clinical characteristics between severe and non-severe patients with COVID-19.
| Variables | All patients (n = 167) |
Disease severity |
||
|---|---|---|---|---|
| Non-severe (n = 137) |
Severe (n = 30) |
P-value | ||
| Age, years | 42.31(15.29) | 40.83(15.47) | 49.03(12.60) | 0.007 |
| Mal sex, n (%) | 95(56.89%) | 75(54.74%) | 20(66.67%) | 0.232 |
| BMI, kg/m2 | 24.52(3.41) | 24.22(22.19,26.12) | 24.55(3.19) | 0.830 |
| Exposure history, n (%) | ||||
| History of cluster onset | 91(54.49%) | NA | NA | NA |
| Exposure to Wuhan | 78(46.71%) | 60(43.80%) | 18(60.00%) | 0.107 |
| Non-exposure to Wuhan | 12(7.19%) | 12(8.76%) | 0(0.00%) | 0.196 |
| Signs and symptoms at admission, n (%) | ||||
| Fingertip oxygen saturation (%) | 98.00(96.00,99.00) | 98.00(97.00,99.00) | 94.00(91.00,97.25) | 0.000 |
| Cough | 132(79.04%) | 106(77.37%) | 26(86.67%) | 0.257 |
| Fever | 146(87.43%) | 118(86.13%) | 28(93.33%) | 0.439 |
| Shortness of breath | 61(36.53%) | 39(28.47%) | 22(73.33%) | 0.000 |
| Sore throat | 25(14.97%) | 21(15.33%) | 4(13.33%) | 1.000 |
| Diarrhea | 56(33.53%) | 50(36.50%) | 6(20.00%) | 0.083 |
| Nausea and vomiting | 17(10.18%) | 16(11.68%) | 1(3.33%) | 0.300 |
| Multiple symptoms | 147(88.02%) | 119(86.86%) | 28(93.33%) | 0.497 |
| Comorbidity, n (%) | ||||
| Any | 44(26.35%) | 30(21.90%) | 14(46.67%) | 0.005 |
| Cardiovascular diseases | 24(14.37%) | 17(12.41%) | 7(23.33%) | 0.209 |
| Diabetes | 11(6.59%) | 4(2.92%) | 7(23.33%) | 0.000 |
| Digestive diseases | 9(5.39%) | 6(4.38%) | 3(10.00%) | 0.430 |
| Respiratory diseases | 4(2.40%) | 2(1.46%) | 2 (6.67%) | 0.148 |
| Central nervous system diseases | 2(1.20%) | 2(1.46%) | 0(0.00%) | 1.000 |
| Hematological diseases | 1(0.60%) | 0(0.00%) | 1(3.33%) | 0.180 |
| Immune diseases | 2(1.20%) | 2(1.46%) | 0(0.00%) | 1.000 |
| Treatment, n (%) | ||||
| Oxygen therapy | 133(79.64%) | 104(75.91%) | 29(96.67%) | 0.011 |
| Mechanical ventilation | 22(13.17%) | 2(1.46%) | 20(66.67%) | 0.000 |
| Invasive | 4(2.40%) | 0(0.00%) | 4(13.33%) | 0.001 |
| Non-invasive | 18(10.78%) | 2(1.46%) | 16(53.33%) | 0.000 |
| Antiviral treatment | 166(99.40%) | 137(100.00%) | 29(96.67%) | 0.180 |
| Glucocorticoids | 42(25.15%) | 20(14.60%) | 22(73.33%) | 0.000 |
| Immunoglobulin | 27(16.17%) | 9(6.57%) | 18(60.00%) | 0.000 |
| Length of stay in hospital | 15.00(12.00,20.00) | 15.00(12.00,20.00) | 17.06(4.98) | 0.260 |
Notes: Data are presented as number (%) or means (standard deviation) or median (interquartile range).
P values indicate differences between severe and non-severe patients.
Abbreviation: COVID-19, Coronavirus disease-19; BMI, Body Mass Index; NA, not applicable.