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. 2020 Mar 10;53(4):e12755. doi: 10.1111/cpr.12755

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© 2020 The Authors. Cell Proliferation Published by John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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OMSCs derived from ageing mice have an intense potential of osteogenesis with PTH treatment. A,B, Western blot analysis showing pCREB and CREB levels in OMSC after treated with PTH at different time points, and quantitative analysis. C,D, ALP staining and osteogenic‐related gene expression analysis after osteogenic induction for 7 days with PTH or vehicle. E,F, ARS and osteogenic‐related gene expression analysis after osteogenic induction for 14 d with PTH or vehicle. N = 3 per group. *P < .05, ***P < .005. All data were expressed as the mean ± SD