Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Mar 30;53(4):e12799. doi: 10.1111/cpr.12799

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2020 The Authors. Cell Proliferation Published by John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

SKA1 accelerates tumour invasion and metastasis via EMT. A and B, Transwell migration and Matrigel invasion assay. sh‐SKA1 infectants exhibited significantly reduced migration and invasion capacity than the sh‐ctr infectants, except for SW1990 cell line. C, Wound‐healing assay measured the effect of SKA1 on PDAC cell motility. Left: Representative images of scratched and recovering of wounded areas taken at different time points. Right: Semi‐quantitative analysis of gap size by ImageJ. The significances were calculated based on the comparison of the control group. *P < .05; **P < .01; ***P < .001. D, Representative haematoxylin‐eosin staining and summarized data on number of metastasis of lung in nude mice at 12 wk after tail vein injection of PANC‐1 or Capan‐1 cells with SKA1 knock‐down or overexpression (n = 10 per group), red arrow, metastatic nodule (P = .033, P = .013, respectively)