Table 2.
iTBS groupa | Baselineb | End of study participation | Follow-up-retreatment request | ||
---|---|---|---|---|---|
2-week (n = 11) | 4-week (n = 7) | 2-week (n = 11)c | 4-week (n = 7)c | ||
PTSD symptom severity | |||||
PCL-5, mean total score (SD) | 49.68 (10.31) | 40.50 (18.83) | 29.14 (12.40) | 46.83 (13.66) | 40.43 (15.91) |
Depressive symptomatology | |||||
IDSSR, mean total score (SD) | 41.02 (11.74) | 33.67 (15.61) | 34.29 (20.42) | 34.25 (15.90) | 52.67 (18.50) |
QIDS, mean total score (SD) | – | – | 15.75 (2.82) | 10.75 (5.25) | |
Elapsed time | |||||
Mean days (SD) | – | – | 88.75 (87.07) | 126.14 (78.32) |
iTBS intermittent theta burst stimulation, SD standard deviation, PTSD post-traumatic stress disorder, PCL-5, PTSD checklist for DSM-5, IDSSR inventory of depressive symptomatology, self-report, QIDS quick inventory of depressive symptoms (self-report)
aGroups (2-week and 4-week) indicate the number of weeks of active iTBS
bBaseline variables are presented as group means; Baseline PCL-5 mean (SD) in the 2-week and 4-week groups were 50.0 (11.4) and 49.4 (9.4), respectively.; Baseline IDSSR scores in the 2-week and 4-week groups were 39.2 (11.50) and 42.8 (11.90), respectively. No significant baseline differences (all p > 0.05) were observed
cDepression rating scale data available from IDSSR (n = 4, 3) and QIDS (n = 8,4) for subjects that completed either 2-weeks or 4-weeks of iTBS, respectively. Whereas at last TBS evaluation, all subjects completed the IDSSR (n = 12 and 7, for 2-weeks or 4-weeks, respectively)