Table 3.
IC50 values (μM) for 7a-u towards human cancer cell lines.
Compound | MCF-7 | HCT-116 | A549 |
---|---|---|---|
7a | 30.24 ± 1.50 | 39.05 ± 0.87 | 45.36 ± 2.13 |
7b | 21.87 ± 1.08 | 36.18 ± 2.32 | 40.68 ± 1.58 |
7c | 14.34 ± 1.51 | 33.28 ± 1.41 | 36.24 ± 1.95 |
7d | 36.13 ± 0.89 | 43.57 ± 1.57 | 51.46 ± 1.66 |
7e | 20.35 ± 0.97 | 35.94 ± 1.18 | 35.85 ± 1.42 |
7f | 25.47 ± 1.23 | 44.23 ± 1.59 | 25.73 ± 1.40 |
7g | 24.98 ± 2.13 | 41.94 ± 2.05 | 24.13 ± 1.64 |
7h | 10.39 ± 1.22 | 35.28 ± 1.53 | 22.96 ± 1.08 |
7i | 33.47 ± 1.78 | 41.66 ± 1.63 | 48.66 ± 1.37 |
7j | 23.45 ± 1.92 | 38.87 ± 2.14 | 39.65 ± 1.82 |
7k | 15.43 ± 1.75 | 33.75 ± 1.57 | 36.54 ± 0.95 |
7l | 19.86 ± 1.36 | 31.77 ± 1.32 | 32.86 ± 1.42 |
7m | 29.05 ± 0.87 | 37.48 ± 1.87 | 38.27 ± 2.24 |
7n | 22.63 ± 1.45 | 30.96 ± 2.36 | 31.44 ± 1.79 |
7o | 26.44 ± 1.48 | 32.27 ± 1.49 | 29.38 ± 1.48 |
7p | 13.60 ± 2.02 | 31.08 ± 1.18 | 30.62 ± 1.32 |
7q | 42.18 ± 1.67 | 13.42 ± 1.32 | 41.23 ± 1.81 |
7r | 39.40 ± 1.89 | 11.94 ± 1.46 | 44.19 ± 1.62 |
7s | 36.58 ± 0.78 | 6.90 ± 1.14 | 34.51 ± 1.08 |
7t | 41.85 ± 2.23 | 22.47 ± 1.70 | 39.98 ± 1.24 |
7u | 40.42 ± 1.81 | 15.39 ± 0.84 | 33.67 ± 1.22 |
Doxorubicin | 19.35 ± 1.18 | 11.26 ± 0.98 | 23.47 ± 1.24 |