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. 2020 Apr 16;10:6491. doi: 10.1038/s41598-020-63100-w

Table 4.

Summary of cases and controls series for French-Canadian BRCA1/2/PALB2 genotyping.

Characteristic Cases Controls
Dates of ascertainment 2000–2016 2009–2015
Ages at ascertainment (mean) 32–89 (60.7) 40–70 (53.2)
Ages of first invasive breast diagnosis (mean) 25–69 (52.7)*
Location of ascertainment Montreal, QC Montreal, QC
Ethnicity French-Canadian French-Canadian‡
Personal history of cancer At least one invasive breast cancer None§
Family history of cancer 55% no, 27% yes, 19% unknown§ None§

*Intervals between ages at first invasive breast cancer and ascertainment range from 0 to 11 years (Mean = 0.67, S.D. = 5.36).

As determined by a review of last names.

As determined by French first language, Canadian origin of all four grandparents, and a city of birth located in Quebec.

§Self-reported data.