Table 4.
Summary of cases and controls series for French-Canadian BRCA1/2/PALB2 genotyping.
| Characteristic | Cases | Controls |
|---|---|---|
| Dates of ascertainment | 2000–2016 | 2009–2015 |
| Ages at ascertainment (mean) | 32–89 (60.7) | 40–70 (53.2) |
| Ages of first invasive breast diagnosis (mean) | 25–69 (52.7)* | – |
| Location of ascertainment | Montreal, QC | Montreal, QC |
| Ethnicity | French-Canadian† | French-Canadian‡ |
| Personal history of cancer | At least one invasive breast cancer | None§ |
| Family history of cancer | 55% no, 27% yes, 19% unknown§ | None§ |
*Intervals between ages at first invasive breast cancer and ascertainment range from 0 to 11 years (Mean = 0.67, S.D. = 5.36).
†As determined by a review of last names.
‡As determined by French first language, Canadian origin of all four grandparents, and a city of birth located in Quebec.
§Self-reported data.