Table 3.
Changes in the AF22 phosphoproteome resulting from 24 h oAβ treatment.
| Identified Proteins | Protein ID | T-Test (p-value) | Fold Change | PTM |
|---|---|---|---|---|
| Isoform 2 of Alpha-tubulin N-acetyltransferase 1 | ATAT_HUMAN | 0.002 | 9.9 | Phosphorylation |
| Eukaryotic translation initiation factor 4B | IF4B_HUMAN | 0.031 | 1.6 | Phosphorylation |
| Isoform 2 of Protocadherin-1 | PCDH1_HUMAN | 0.014 | 11.0 | Phosphorylation |
| Isoform 3 of Periphilin-1 | PPHLN_HUMAN | 0.022 | 1.7 | Phosphorylation |
| Isoform 3 of RNA-binding protein with serine-rich domain 1 | RNPS1_HUMAN | 0.043 | 0.4 | Phosphorylation |
The provided table depicts proteins with significant changes in expression (p < 0.05, T-test with Benjamini-Hochberg correction) in the phosphoproteome of AF22 cells challenged with oAβ relative to untreated AF22 cells. The proteins detailed in this table were identified after enrichment with TiO2. n = 11 (control), n = 8 (oAβ treated).