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. 2020 Jan 17;45(6):1059–1067. doi: 10.1038/s41386-020-0614-2

Fig. 4. mTOR protein expression and phosphorylation in mTORC1 and mTORC2.

Fig. 4

mTOR complexes were co-immunoprecipitated from comparison and schizophrenia DLPFC. a mTORC1 was co-immunoprecipitated using Raptor, and b mTOR expression and c phosphorylation status (S2448) was assessed by western blot analysis. d mTORC2 was co-immunoprecipitated using Rictor, and similarly, e mTOR expression, and f phosphorylation status was evaluated. We observed increased mTOR expression in both mTORC1 and mTORC2 in schizophrenia. *p ≤ 0.05.