FIG 10.

Pathology analysis of EV71- or CA16-infected neonatal mice. One-day-old ICR mice were intracerebrally inoculated with EV71 CC063 (10^5.5 CCID₅₀/ml), CA16 CC045 (10^2.7 CCID₅₀/ml), or DMEM (mock control). At 1 h postchallenge, FNC or DMSO was injected intraperitoneally, as described in Materials and Methods. (A and B) Representative images from the lung (a to c), brain (d to f), spine skeletal muscle (g to i), and hind-limb muscle (j to l) postinfection are shown for EV71-infected (A) or CA16-infected (B) mice. The images for noninfected mice were used as a control (a, d, g, and j in panels A and B). Magnification, ×400.