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. 2011 Jan 19;2011(1):CD003626. doi: 10.1002/14651858.CD003626.pub2

Comparison 2. Sensitivity analyses.

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Mortality ‐ Duration of the treatment with UDCA 8 592 Risk Ratio (M‐H, Fixed, 95% CI) 1.00 [0.46, 2.20]
1.1 Short treatment duration (less than 24 months) 2 34 Risk Ratio (M‐H, Fixed, 95% CI) 0.43 [0.02, 9.00]
1.2 Long treatment duration (24 months or more) 6 558 Risk Ratio (M‐H, Fixed, 95% CI) 1.08 [0.48, 2.44]
2 Mortality ‐ Dose of UDCA in the treatment 8 592 Risk Ratio (M‐H, Fixed, 95% CI) 1.00 [0.46, 2.20]
2.1 Low dose of UDCA (less than 13 mg/kg body weight /day) 3 78 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
2.2 High dose of UDCA (13 mg/kg body weight/day or more) 5 514 Risk Ratio (M‐H, Fixed, 95% CI) 1.00 [0.46, 2.20]
3 Mortality ‐ Different duration of the treatment with different dose of UDCA 8 592 Risk Ratio (M‐H, Fixed, 95% CI) 1.00 [0.46, 2.20]
3.1 Short treatment duration with low dose of UDCA 1 20 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
3.2 Short treatment duration with high dose of UDCA 1 14 Risk Ratio (M‐H, Fixed, 95% CI) 0.43 [0.02, 9.00]
3.3 Long treatment duration with low dose of UDCA 2 58 Risk Ratio (M‐H, Fixed, 95% CI) 0.0 [0.0, 0.0]
3.4 Long treatment duration with high dose of UDCA 4 500 Risk Ratio (M‐H, Fixed, 95% CI) 1.08 [0.48, 2.44]