Data Base	Time span	Search Strategy
The Cochrane Hepato‐Biliary Group Controlled Trials Register	October 2010.	('primary sclerosing cholangitis' OR PSC) AND ('bil* acid*' OR 'lithocolic acid*' OR LCA OR 'chenodeoxycholic acid*' OR CDCA OR 'ursodeoxycholic acid*' OR UDCA OR 'deoxycholic acid*' OR DCA OR 'dehydrocholic acid*' OR DHCA OR 'tauro‐ursodeoxycholic acid*' OR TDCA)
The Cochrane Central Register of Controlled Trials in The Cochrane Library	Issue 4, 2010	#1 MeSH descriptor Cholangitis, Sclerosingexplode all trees #2 primary sclerosing cholangitis or PSC #3 (#1 OR #2) #4 MeSH descriptor Bile Acids and Saltsexplode all trees #5 bil* acid* or lithocolic acid* or LCA or chenodeoxycholic acid* or CDCA or ursodeoxycholic acid* or UDCA or deoxycholic acid* or DCA or dehydrocholic acid* or DHCA or tauro‐ursodeoxycholic acid* or TDCA #6 (#4 OR #5) #7 (#3 AND #6)
MEDLINE (Ovid SP)	1950 to October 2010.	1. exp Cholangitis, Sclerosing/ 2. (primary sclerosing cholangitis or PSC).mp. [mp=title, original title, abstract, name of substance word, subject heading word, unique identifier] 3. 1 or 2 4. exp "Bile Acids and Salts"/ 5. (bil* acid* or lithocolic acid* or LCA or chenodeoxycholic acid* or CDCA or ursodeoxycholic acid* or UDCA or deoxycholic acid* or DCA or dehydrocholic acid* or DHCA or tauro‐ursodeoxycholic acid* or TDCA).mp. [mp=title, original title, abstract, name of substance word, subject heading word, unique identifier] 6. 4 or 5 7. 3 and 6 8. (random* or blind* or placebo* or meta‐analysis).mp. [mp=title, original title, abstract, name of substance word, subject heading word, unique identifier] 9. 7 and 8
EMBASE (Ovid SP)	1980 to October 2010.	1. exp primary sclerosing cholangitis/ 2. (primary sclerosing cholangitis or PSC).mp. [mp=title, abstract, subject headings, heading word, drug trade name, original title, device manufacturer, drug manufacturer name] 3. 1 or 2 4. exp bile acid/ 5. (bil* acid* or lithocolic acid* or LCA or chenodeoxycholic acid* or CDCA or ursodeoxycholic acid* or UDCA or deoxycholic acid* or DCA or dehydrocholic acid* or DHCA or tauro‐ursodeoxycholic acid* or TDCA).mp. [mp=title, abstract, subject headings, heading word, drug trade name, original title, device manufacturer, drug manufacturer name] 6. 4 or 5 7. 3 and 6 8. (random* or blind* or placebo* or meta‐analysis).mp. [mp=title, abstract, subject headings, heading word, drug trade name, original title, device manufacturer, drug manufacturer name] 9. 7 and 8
Science Citation Index Expanded (http://apps.isiknowledge.com)	1900 to October 2010.	# 5 #4 AND #3 # 4 TS=(random* or blind* or placebo* or meta‐analysis) # 3 #2 AND #1 # 2 TS=(bil* acid* or lithocolic acid* or LCA or chenodeoxycholic acid* or CDCA or ursodeoxycholic acid* or UDCA or deoxycholic acid* or DCA or dehydrocholic acid* or DHCA or tauro‐ursodeoxycholic acid* or TDCA) # 1 TS=(primary sclerosing cholangitis or PSC)