Outcome	Available case analysis risk ratio (95% CI)	Assumption about missing data	Risk ratio (95% CI) under this assumption
3+ lines at 6 months	0.755 (0.556, 1.025)	IMOR ½ 2	0.7 (0.516, 0.949)
3+ lines at 24 months	0.81 (0.636, 1.033)	IMOR ½ 2	0.768 (0.593, 0.994)
6+ lines at 6 months	0.423 (0.191, 0.934)	IMOR 2 ½	0.488 (0.225, 1.055)
6+ lines at 24 months	0.811 (0.638, 1.032)	IMOR ½ 2	0.741 (0.58, 0.947)