Table 2.

Mutation Rates of Microsatellites in MMR-Deficient Cells

Microsatellites	Mutation rates		P valuea
	-1 bp OF system, means ± SEM	+1 bp OF system, means ± SEM
D9S242 (AAAG)18	34.5 × 10-4 ± 0.06 × 10-4	36.6 × 10-4 ± 0.04 × 10-4	.0012
D9S242 (AAAG)15	23.4 × 10-4 ± 0.83 × 10-4	32.0 × 10-4 ± 0.90 × 10-4	.0198
D9S242 (AAAG)12	16.4 × 10-4 ± 1.51 × 10-4	15.2 × 10-4 ± 1.08 × 10-4	.5983

NOTE. Mutation rates were calculated by the Ma-Sandri-Sarkar Maximum Likelihood Estimator method and corrected for their negative controls. Rates are expressed as mutations at microsatellite sequence per cell per generation.

OF, out-of-frame.

^aBetween mutation rates of -1 bp OF and +1 bp OF systems.