Table 6.
Gene ontology analysis of up- and down-regulated genes (related with immune and inflammation) from miR-19-expressing A549 cells to vector-expressing A549 cells
| GO ID | Biological process | Count | p-value | q-value |
|---|---|---|---|---|
| GO:0006954 | inflammatory response | 20 | 1.83E-25 | 5.78E-25 |
| GO:0006958 | complement activation, classical pathway | 4 | 1.60E-07 | 1.01E-07 |
| GO:0045087 | innate immune response | 4 | 1.00E-04 | 2.77E-05 |
| GO:0006955 | immune response | 8 | 1.21E-04 | 3.28E-05 |
| GO:0006957 | complement activation, alternative pathway | 2 | 2.74E-04 | 6.69E-05 |
| GO:0030101 | natural killer cell activation | 2 | 5.45E-04 | 1.19E-04 |
| GO:0002842 | positive regulation of T cell mediated immune response to tumor cell | 1 | 0.003256 | 4.26E-04 |
| GO:0002378 | immunoglobulin biosynthesis | 1 | 0.003256 | 4.26E-04 |
| GO:0002862 | negative regulation of inflammatory response to antigenic stimulus | 1 | 0.00488 | 5.70E-04 |
| GO:0002863 | positive regulation of inflammatory response to antigenic stimulus | 1 | 0.006502 | 6.77E-04 |
| GO:0050729 | positive regulation of inflammatory response | 1 | 0.033668 | 0.002274 |
| GO:0045089 | positive regulation of innate immune response | 1 | 0.036815 | 0.002446 |
| GO:0002768 | immune response-regulating cell surface receptor signaling pathway | 1 | 0.044637 | 0.002855 |