Table 10.
Information on the core targets relevant to TM-JH.
| Target name | Protein name | Degree | Average shortest path length | Betweenness centrality | Closeness centrality | Clustering coefficient | MCODE score |
|---|---|---|---|---|---|---|---|
| APP | Amyloid-beta precursor protein | 6 | 1.25 | 0.24 | 0.80 | 0.47 | 1.80 |
| ACE | Angiotensin-converting enzyme | 6 | 1.25 | 0.15 | 0.80 | 0.60 | 1.61 |
| PTGS2 | Prostaglandin G/H synthase 2 | 6 | 1.25 | 0.17 | 0.80 | 0.53 | 1.71 |
| MMP9 | Matrix metalloproteinase-9 | 5 | 1.38 | 0.06 | 0.73 | 0.70 | 1.71 |
| LDLR | Low-density lipoprotein receptor | 4 | 1.50 | 0.06 | 0.67 | 0.67 | 1.80 |
| NOS2 | Nitric oxide synthase, inducible | 4 | 1.63 | 0.01 | 0.62 | 0.83 | 1.80 |
| NOS1 | Nitric oxide synthase, brain | 3 | 1.75 | 0.00 | 0.57 | 1.00 | 1.80 |