Table 9.
Information on core targets relevant to TM-CX.
Target name | Protein name | Degree | Average shortest path length | Betweenness centrality | Closeness centrality | Clustering coefficient | MCODE score |
---|---|---|---|---|---|---|---|
PTGS2 | Prostaglandin G/H synthase 2 | 7 | 1.36 | 0.22 | 0.73 | 0.38 | 1.57 |
NOS2 | Nitric oxide synthase, inducible | 3 | 2.00 | 0.00 | 0.50 | 1.00 | 1.80 |
NOS1 | Nitric oxide synthase, brain | 3 | 2.00 | 0.00 | 0.50 | 1.00 | 1.80 |
APP | Amyloid-beta precursor protein | 8 | 1.27 | 0.43 | 0.79 | 0.25 | 1.80 |
F2 | Prothrombin | 4 | 1.64 | 0.18 | 0.61 | 0.50 | 1.80 |
ACE | Angiotensin-converting enzyme | 6 | 1.45 | 0.16 | 0.69 | 0.47 | 1.57 |