Antibacterial effect in vivo and biocompatibility assay. (A) Photomicroscope images of wounds at different days. H&E staining. (B) Heart. (C) Liver. (D) Spleen. (E) Lung. (F) Kidney. (G) Subcutaneous. (H) Wound areas. (I) Infected skin tissue. (J) Infected skin treated with SiO2-PCe6-IL2. (K) Cytotoxicity. (L) Hemolysis rate. (M) Wound healing rate. (N) The number of bacterial colony-forming units obtained from control, and after treated by Ce6, SiO2-PCe6-IL1, SiO2-PCe6-IL2 with illumination for 15 min (50 µL of Ce6, SiO2-PCe6-IL and SiO2-PCe6-IL2 (containing 100 µM Ce6), 5 mW/cm2).