Table 1.
Correlation between SLeA and STn tissue expression and clinicopathologic variables of gastroesophageal and colorectal tumors.
| Tumor Type | Antigen/ Antibody | N | Outcome | Ref |
|---|---|---|---|---|
| Esophageal Cancer (SCC) | SLeA /NS19-9 | 54 | - | 111 |
| SLeA /CA19.9 | 74 | Tumor differentiation (P < 0.05) Poor prognosis (P < 0.05) |
112 | |
| SLeA /Anti-SLeA | 125 | Hematogenous recurrence (p=0.026) Distant lymph node metastasis | 113 | |
| STn/ B72.3 | 84 | - | 94 | |
| SLeA /CA19.9 | 115 | Stromal type of staining: Depth of invasion Tumor size | 114 | |
| SLeA /CA19.9 | 52 | Stromal type of staining: Peritoneal dissemination (P < 0.05) Lymphatic invasion (P < 0.05) |
96 | |
| STn/ B72.3 and TKH2 | 52 | Stromal type of staining: Peritoneal dissemination in undifferentiated tumors (P < 0.05) | 96 | |
| Gastric cancer | STn/ C 1282 | 242 | Overall survival of stage I patients (P= 0.002) Prognosis (P=0.005) |
97 |
| STn/ HB-STn1 | 211 | Venous invasion (P < 0.05) Overall survival (P < 0.05) Prognosis (P=0.042) |
98 | |
| STn/ TKH2 | 60 | Depth of invasion (P< 0.01) Tumor stage (P< 0.01) Lymph node metastasis (P< 0.005) Lymphatic invasion (P< 0.05) 5-year survival of advanced cases (P< 0.01) |
58 | |
| STn/ TKH2 | 54 | - | 99 | |
| SLeA/CSLEA1 | 62 | - | 119 | |
| SLeA /NS19-9 | 309 | Lymph node metastasis (P < 0.005) Recurrence (P < 0.005) Postoperative survival (P < 0.001 |
116 | |
| SLeA /CA19.9 | 52 | - | 117 | |
| Unspecified | 149 | Histological type (P< 0.05) Depth of invasion (P< 0.05) Lymph node metastasis (P< 0.05) Venous invasion (P< 0.05) Astler-Coller stage (P< 0.05) TNM stage (P< 0.05) Recurrence (P< 0.01) 5-year survival (P< 0.01) |
115 | |
| SLeA /NS19-9 | 52 | 5-year survival (P< 0.05) | 110 | |
| Colorectal cancer | SLeA /NS19-9 | 368 | 5-year disease-free survival (P=0.012) Recurrence |
118 |
| STn/ TKH2 | 52 | - | 110 | |
| STn/ TKH2 | 142 | Depth of invasion | 99 | |
| STn/ HB-STn1 | 152 | TNM classification (P=0.025) AJCC classification (P=0.049) in transitional tissue |
103 | |
| STn/ B72.3 | 234 | Histological differentiation (P=0.006) Perineural invasion (P=0.041) | 104 | |
| STn/ C 1282 | 239 | Age (P=0.024) | 105 | |
| STn/ TKH2 | 111 | - | 106 |
-No correlation to clinicopathological variables was found