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. 2020 Apr 6;10(11):5029–5047. doi: 10.7150/thno.42440

Table 1.

Correlation of intra-tumoral SC density with clinicopathological features in PDAC samples

Variables Number of cases Low GFAP+/ S100+ group High GFAP+/ S100+ group p value
Age (years)
≤ 60 26 9 (11.3%) 17 (21.3%) 0.057
>60 54 31 (38.8%) 23 (28.8%)
Gender
Male 43 19 (23.8%) 24 (30%) 0.268
Female 37 21 (26.3%) 16 (20%)
Histological grade
Well 13 5 (6.3%) 8 (10%) 0.104
Moderate 49 23 (28.8%) 26 (32.5%)
Poor 18 12 (15%) 6 (7.5%)
Lymph node metastasis
No 31 15 (18.8%) 16 (20%) 0.821
Yes 49 25 (31.3%) 24(30%)
Distant metastases
No 65 36 (45%) 29 (36.3%) 0.046*
Yes 15 4 (5%) 11 (13.8%)
TNM stage
Ⅰ-Ⅱ 57 28 (35%) 29 (36.3%) 0.808
Ⅲ-Ⅳ 23 12 (15%) 11 (13.8%)
Vascular invasion
No 56 33 (41.3%) 23 (28.8%) 0.014*
Yes 24 7 (8.8%) 17 (21.3%)
Perineural invasion
No 38 24 (30%) 14 (17.5%) 0.025*
Yes 42 16 (20%) 26 (32.5%)

*Denotes statistical significance. *p < 0.05