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. 2017 Mar 1;45(7):614–620. doi: 10.1002/dc.23697

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© 2017 Wiley Periodicals, Inc.

This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.

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(A) Herpes simplex virus (HSV) inclusions in a bronchial washing cytology specimen. The left image shows infected bronchial epithelial cells with nuclei that have a glassy appearance due to viral cytopathic effect (Papanicolaou stain, 400×). The right image shows a cell block preparation of this sample demonstrating both Cowdry type A (black arrow) and Cowdry type B (yellow arrow) intranuclear inclusions (H&E stain, 400×). (B) Lung adenocarcinoma in a sputum specimen. The cluster of carcinoma cells shown has prominent nucleoli that may mimic viral infection (Papanicolaou stain, 400×). (C) Immunohistochemistry for HSV shows several scattered infected cells (positive red stain) in this lung sample from a lymphoma patient (immunohistochemical stain, 200×). [Color figure can be viewed at http://wileyonlinelibrary.com]