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. 2007 Feb 6;16(3):171–178. doi: 10.1111/j.1600-0625.2006.00527.x

Figure 2.

Figure 2

 Oxymetazoline suppresses T‐cell proliferation induced by anti‐CD3/anti‐CD28 mAb stimulation. PBMC were isolated from buffy coats of healthy volunteers. 2 × 105 cells/well were stimulated using 1 μg/ml of anti‐CD3 and 2 μg/ml anti‐CD28 mAb in the presence/absence of titrated concentrations of oxymetazoline (OMZ). Proliferation was measured after 4 days of culture plus an additional 16 h in the presence of 37 kBq [3H]‐thymidine. Results of four independent experiments/donors are shown (mean ± standard deviation, n = 4).