Figure 1.

Serum amyloid A (SAA) as a multifunctional protein in modulating the inflammatory response. IL‐6 produced by macrophages after local stimulation promotes the hepatic production of SAA which has roles in inhibition of lymphocyte proliferation, neutrophil activities, adhesion of T lymphocytes to extracellular matrix, platelet aggregation and induction of adhesion, migration and tissue infiltration of monocytes, neutrophils and prostaglandin synthesis (This figure was prepared using Servier Medical Art. https://smart.servier.com/).