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. 2020 Jan 4;26(5):576–588. doi: 10.1111/cns.13283

Table 2.

Demographic and neuropsychological data

Items HC (n = 23) WMH F/χ 2 P Post hoc analyses
NC (n = 19) MCI (n = 22) HC VS WMH‐NC HC VS WMH‐MCI WMH‐NC VS WMH‐MCI
Demographics
Age (y) 62.3 ± 1.50 67.1 ± 1.66 65.1 ± 1.54 2.311 .108b
Education (y) 12.7 ± 0.67 11.7 ± 0.73 11.00 ± 0.68 1.599 .210b
Gender (male/female) 12/11 9/10 9/13 0.576 .750a
General cognition
MMSE 29.2 ± 0.31 28.6 ± 0.34 27.3 ± 0.32 9.653 <.001b, * 0.206 <0.001* 0.006*
MoCA‐BJ 26.7 ± 0.36 26.4 ± 0.40 21.5 ± 0.37 61.959 <.001b, * 0.667 <0.001* <0.001*
Composition Z scores of each cognitive domain
Episodic Memory 0.45 ± 0.14 0.05 ± 0.16 −0.51 ± 0.15 11.137 <.001b, * 0.065* <0.001* 0.011*
AVLT‐DR 0.35 ± 0.19 0.32 ± 0.21 −0.64 ± 0.19 8.626 .001b, * 0.896 <0.001* 0.001*
VR‐DR (WMS) 0.54 ± 0.19 −0.22 ± 0.21 −0.37 ± 0.20 6.192 .004b, * 0.011* 0.002* 0.593
Information Processing Speed 0.27 ± 0.17 0.18 ± 0.19 −0.44 ± 0.18 4.816 .011b, * 0.720 0.005* 0.020*
TMT‐A (inverse) 0.45 ± 0.20 −0.02 ± 0.22 −0.45 ± 0.2 5.138 .009b, * 0.120 0.002* 0.142
Stroop A (inverse) 0.20 ± 0.20 0.24 ± 0.22 −0.41 ± 0.21 3.026 .056b
Stroop B (inverse) 0.17 ± 0.20 0.31 ± 0.22 −0.45 ± 0.21 3.729 .030b, * 0.640 0.035* 0.015*
Language 0.25 ± 0.13 −0.08 ± 0.19 −0.19 ± 0.18 1.678 .195
CVF 0.01 ± 0.21 0.11 ± 0.23 −0.11 ± 0.22 0.229 .796
BNT 0.48 ± 0.20 −0.26 ± 0.22 −0.28 ± 0.20 4.661 .013b, * 0.014* 0.009* 0.961
Executive Function 0.20 ± 0.14 0.12 ± 0.16 −0.32 ± 0.14 3.741 .029b, * 0.581 <0.001* <0.001*
DST‐backward 0.11 ± 0.21 0.02 ± 0.23 −0.13 ± 0.22 0.320 .727
TMT‐B (inverse) 0.52 ± 0.19 −0.01 ± 0.21 −0.54 ± 0.19 7.490 .001b, * 0.239 <0.001* <0.001*
Stroop C (inverse) −0.02 ± 0.21 0.35 ± 0.26 −0.28 ± 0.21 2.152 .125

Values are presented as the mean ± standard error (SE).

Abbreviations: AVLT‐DR, Auditory Verbal Learning Test‐delayed recall; BNT, Boston Naming Test; CVF, category verbal fluency; DST, Digit Span Test; HC, health control; MCI, mild cognitive impairment; MMSE, mini mental state examination; MoCA‐BJ, Beijing version of the Montreal Cognitive Assessment; NC, normal cognition; Stroop A, B and C, Stroop Color and Word Tests A, B, and C; TMT‐A and TMT‐B, Trail Making Test‐A and B; VR‐DR, visual reproduction‐delay recall; WMH, white matter hyperintensities; WMS, Wechsler Memory Scale.

a

The p value was obtained by χ 2 test.

b

The p value was obtained by one‐way ANOVA.

*

Indicates a statistical difference between groups, P < .05.