Table 1.
Examples of different types of nuclear transport signals
| Amino acid sequence | Protein | Type of signal | References |
|---|---|---|---|
| PKKKRKV | SV40 T antigen | Classical NLS | 33 |
| KRx{10}KKKL | Nucleoplasmin | Bipartite NLS | 31, 33 |
| VRILESWFAKNIENPYLDT | Matα2 | Polar/nonpolar residues NLS | 196 |
| PAAKRVKLD | c‐Myc | cMyc‐NLS | 197 |
| YNDFGNYNNSSNFGPMKGGNFGGRSSGPYGGGGQY | hnRNP A1 (M9 sequence hydrophobic subclasses) | hPY‐NLS | 198 |
| KVSRRG‐GHQNSYKPY | hnRNP D (basic enriched) | bPY‐NLS | 45 |
| RQARRNRRRRWR | VIH Rev protein | Arginine‐rich NLS | 199 |
| DNSQRFTQRGGGAVGKNRRGGRGGNRGGRNNNSTRFNPLAK | Nab2p | Arginine/glycine‐rich NLS | 200 |
| KTPGKKKKGK | Parathyroid hormone‐related protein (PTHrP) | Lysine‐rich‐NLS | 201 |
| QDLNSTAAPHPRLSQYKSKYSSLEQSERRRRL | Snurportin1 | UsnRNPs‐NLS | 202 |
| LPPLERLTL | HIV Rev | Hydrophobic‐NES | 32 |
| LALKLAGLKI | PKI | NES | 35, 203 |
| LCQAFSDVIL | Cyclin B1 | NES | |
| LQKKLEELEL | MAPKK | NES | 204 |
| LAEMLEDLHI | NMD3 | NES | 77 |
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