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PfA‐M1 in complex with potent inhibitor. The designed inhibitor 10o (purple stick representation), coordinates the catalytic zinc ion (gray sphere) through a hydroxamic acid, and occupies both the S1 and S1′ subsites 32. Key PfA‐M1 active site residues lining the subsites are shown as gray sticks, with those of the zinc‐binding motif colored wheat.
