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. 1998 Oct 1;12(13):1255–1265. doi: 10.1096/fasebj.12.13.1255

Table 2.

Compilation of several diseases reported to be possibly associated with mechanism of molecular mimicry

Disease Cross‐reactive immune responses References
Primary biliary cirrhosis Pyruvate dehydrogenase complex Anti‐mitochondrial response HLA DRa Microorganisms: E. coli, S. cerevisial 6366
Rasmussen's encephalitis Antiglutamate receptor (GLUR3) response Microorganisms 66, 67
Multiple sclerosis Myelin proteins Viruses: corona, measles, mumps, EBV, herpes, etc. 18, 19, 47, 6871
Myasthenia gravis Acetylcholine receptor Neurofilaments Herpes 39, 72, 73
Guillain‐Barre Peripheral nerve Gangliosides Campylobacter jejuni 7476
Insulin‐dependent diabetes Islet antigens (GAD 65, proinsulin carboxypeptidase H) Coxsackie B Rotaviruses Hepatitis C, herpes, rhino‐, hanta‐, and faviviruses Retroviral 40, 7780
Myocardial (heart) ADP/ATP carrier protein Cardiac myosin Myocardial cell surface protein Coxsackie B3, streptococci 3537, 81, 82
Celiac Gliadin Enterocyte surface molecules Adenoviruses Enteric microbes 83, 84
Graft vs. host transplantation Aminopeptidase N HLA molecule Cytomegalovirus 85, 86
Pemphigus Desmosomes VH‐CDR3 87
Herpes stomal keratitis Herpes simplex Corneal antigen(s) 88
Autoimmune uveitis S‐antigen IRBP Viruses 38, 89
Peptic ulcer/gastric CA H. pylori Self antigens on gastric mucosa 90
Pathogenesis in:
HIV 9194
Lyme disease 95
Streptococcal 82, 96
Syphilis 97
Prion protein disease 98
Trypanosoma 99102