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. 2011 Aug 16;585(19):2935–2942. doi: 10.1016/j.febslet.2011.08.012

Fig. 6.

Fig. 6

Effect of overexpression of chimeras in Bax and Bak oligomerization. HEK293 cells were transfected with vectors encoding myc-mRFP-TMD Bcl-XL, myc-mRFP-TMD VAMP2 or myc-mRFP, treated with 30 μM camptothecin for 24 h and the effect on Bax and Bak oligomerization analyzed by crosslinking with BSOCOES. Fractions from each sample were analyzed by western blot using antibodies against Bax, Bak or myc (to detect overexpressed proteins). Sizes of molecular mass markers run alongside are indicated on the left in kDa. −, without BSOCOES; +, with BSOCOES.