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Comparison of PILS‐AP with the other M1 family members. Alignment of the primary sequences in the most conserved region surrounding the known catalytic residues, Zn ligands and the substrate binding Glu (marked by asterisks). Identical residues conserved in all M1 members are shaded. For clarity, the less homologous sequences of aminopeptidase B and leukotriene‐A4 hydrolase have been omitted. IRAP, insulin‐regulated aminopeptidase; AP‐N, AP‐A, aminopeptidases N and A, respectively.
