Table 2.
Calculated dipole moments of various trimeric viral fusion TM proteins
| PDB code | Virus | Viral family | Atoms (n)a | Residue length of HR1/HR2 | Dipole moment (Debye)a |
|---|---|---|---|---|---|
| pH‐dependent fusion | |||||
| 4JPR | ASLV | α‐Retroviridae | 687 | 39/16 | 621 |
| 3MK0 | LCMV | Arenaviridae | 875 | 48/14 | 850 |
| 1HTM | IAV | Orthomyxoviridae | 989 | 65/17 | 802 |
| 2EBO | EBOV | Filoviridae | 601 | 36/14 | 261 |
| 4G2K | MARV | Filoviridae | 662 | 41/15 | 262 |
| pH‐independent fusion | |||||
| 1MG1 | HTLV‐1 | δ‐Retroviridae | 663 | 46/8 | 176 |
| 2XZ3 | BLV | δ‐Retroviridae | 746 | 52/8 | 232 |
| 1Y4M | HERV‐FRD | γ‐Retroviridae | 399 | 31/0b | 275 |
| 1MOF | MoMLV | γ‐Retroviridae | 418 | 33/0b | 210 |
aCalculated for a single‐fusion TM monomer. bHR2 helix is disordered in the crystal structure.