Table 3.

Overview of p62-interacting proteins and associated signaling pathways that determine cancer cell fate

Domain	Partner molecules	Signaling	Cell survival/death	References
ZZ	RIP1	NF-κB	Survival	[31]
TB	TRAF6	NF-κB	Survival	[52]
KIR	Keap1	Keap1-Nrf2	Survival	[70]
UBA	Caspase 8	Autophagy	Death	[33, 78]
	VDAC	Mitophagy	Survival	[43]
168–224	EGFR	ERFR/Autophagy	Death	[98]