Table 1.
p16 IHC and CDKN2A FISH data for all informative samples from 243 patients
| p16 status (IHC) | CDKN2A copy number (FISH) | ||||
|---|---|---|---|---|---|
| n (%) | n (%) | n (%) | |||
| Positive | 141 (47) | Normal | Disomy | 107 (39) | |
| Negative | 162 (53) | Copy number loss | 138 (50) | Monosomy | 46 (17) |
| Total | 303 | Deletion (hetero) | 44 (16) | ||
| Deletion (homo) | 48 (17) | ||||
| Copy number gain | 29 (11) | Amplification | 1 (1) | ||
| Polysomy | 28 (10) | ||||
| Total | 274 | ||||
Results were available for both p16/CDKN2A IHC and FISH for at least one sample from 243 of 320 patients. Copy number loss is represented by monosomy, heterozygous deletion, or homozygous deletion. Copy number gain is represented by amplification or polysomy.