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. 2020 Apr 8;368(6494):1016–1020. doi: 10.1126/science.abb7015

Fig. 3. Transmission of SARS-CoV-2 in cats.

Fig. 3

Transmission of the CTan-H virus strain was evaluated in subadult cats (A to D) and juvenile cats (E to G). (A) Viral RNA in the feces of virus-inoculated or virus-exposed subadult cats. (B) Viral RNA in tissues or organs of inoculated or exposed subadult cats euthanized on day 11 p.i. (pair 1, red bars) or day 12 p.i. (pairs 2 and 3). Antibodies against SARS-CoV-2 in these euthanized subadult cats were detected by ELISA (C) and neutralization assay (D). (E) Viral RNA in nasal washes of juvenile cats. Sera from juvenile cats were collected on day 20 p.i., except for sera from one virus-inoculated animal that died on day 13 p.i. Antibody values for this cat (indicated by asterisks) were detected from sera collected on day 10 p.i.; antibodies against SARS-CoV-2 were detected by ELISA (F) and neutralization assay (G). Each color bar represents the value from an individual animal. The horizontal dashed lines in (C) and (F) show the cutoff value for seroconversion, and the horizontal dashed lines in the other panels indicate the lower limit of detection.