Table 4b.
Aramchol (n=19) | Placebo (n=20) | Difference | |||||
---|---|---|---|---|---|---|---|
Baseline | Posttreatment | P-Value | Baseline | Posttreatment | P-Value | P-Value | |
VAT (l) | 6.1 (2.8) | 5.6 (3.0) | 0.5533 | 6.7 (2.7) | 6.4 (2.3) | 0.6280 | 0.6118 |
ASAT (l) | 7.9 (4.7) | 8.2 (5.9) | 0.9530 | 8.1 (4.3) | 8.1 (3.9) | 0.6507 | 0.4959 |
VAT + ASAT (l) | 14.6 (4.3) | 14.3 (4.9) | 0.9323 | 14.9 (4.2) | 15.3 (4.1) | 0.7906 | 0.4634 |
Visceral fat ratio (%) | 42.1 (18.9) | 40.9 (13.5) | 0.9323 | 44.1 (15.6) | 44.0 (15.5) | 0.5678 | 0.9403 |
Thigh volume (l) | 12.6 (1.8) | 12.5 (1.5) | 0.4037 | 11.8 (2.9) | 11.7 (2.9) | 0.8063 | 0.4447 |
Muscle ratio (kg/l) | 7.2 (1.2) | 7.1 (1.1) | 0.3894 | 7.7 (2.3) | 7.7 (1.9) | 0.8176 | 0.3661 |
Fat storage (l/m2) | 5.0 (1.3) | 5.0 (1.6) | 0.8900 | 5.0 (1.8) | 5.0 (1.2) | 0.3529 | 0.8737 |
Visceral Fat Index (l/m2) | 2.0 (0.7) | 1.9 (0.9) | 0.6685 | 2.3 (0.6) | 2.1 (0.6) | 0.2121 | 0.7221 |
Fat ratio (%) | 53.2 (7.3) | 52.9 (8.1) | 0.8904 | 54.4 (11.9) | 55.0 (9.5) | 0.9661 | 0.3584 |
Pericardial Volume (mm3) | 183300 (103100) | 202800 (75900) | 0.2500 | 136500 (72019) | 171050 (176500) | 0.0134 | 0.1633 |
Data are expressed as median (IQR) with p-values from Wilcoxon signed rank test or mean difference with P-value from t-test in parentheses. N’s are “best case” P-values in bold denote statistical significance < 0.05.