Table 1. Sedation scores obtained over time using a 5-point simple descriptive scale (adapted from Steagall et al., 2009).

Time-point	Sedation scores		Median of the differences	95% CI of the differences	p value
	Median (range)	Interquartile range
Baseline	0 (0–2)	[0–0]	–	–	–
15 min	1 (0–2)*	[0–2]	0	0 to 1	0.012
0.5 h	1 (0–3)*	[1–1]	1	1 to 1	<0.001
1 h	1 (0–3)	[0–2]	0	0 to 1	0.053
2 h	1 (0–3)	[0–2]	0	0 to 1	0.051
3 h	0 (0–3)	[0–2]	0	0 to 0	0.161
4 h	0 (0–3)	[0–2]	0	0 to 0	0.155
6 h	0 (0–3)	[0–2]	0	0 to 0	>0.999
8 h	0 (0–3)	[0–2]	0	0 to 0	>0.999
12 h	0 (0–3)	[0–0]	0	0 to 0	>0.999
24 h	0 (0–2)	[0–0]	0	0 to 0	>0.999

Notes.

Scores were obtained at baseline, 15 min after sedation with acepromazine-buprenorphine, and between 0.5 to 24 h after extubation. Scores over time were compared with baseline using Friedman test and Dunn’s multiple comparisons test. Sedation scores are presented as median (range) and interquartile range. Median of the differences (in comparison with baseline) and their 95% confidence interval (CI) are presented.

^*Significantly different from baseline (p < 0.05).