Table 3. The expression of genes with rare variants identified in ES analysis.
| Pathway | Gene symbol/ variant |
KC_15 | KC_16 | KC_17 | KC_18 | KC_19 | Mean expression |
|---|---|---|---|---|---|---|---|
| Wnt Signaling |
WNT1 c.1063G>T |
0.051 | 0.000 | 0.000 | 0.018 | 0.023 | 0.0103 |
| Focal Adhesion |
PTK6 c.1066C>A |
27.705 | 31.413 | 22.991 | 25.809 | 26.031 | 26.5610 |
| Wnt Signaling |
FZD2 c.1238G>A |
1.254 | 0.151 | 2.988 | 0.453 | 0.544 | 1.3098 |
| Wnt Signaling |
VANGL1 c.41C>T |
4.655 | 3.581 | 4.129 | 3.132 | 5.074 | 4.2475 |
| Focal Adhesion |
COL4A4 c.2347G>A |
8.802 | 8.487 | 15.100 | 5.863 | 7.398 | 9.2908 |
| Wnt Signaling |
LRP6 c.4822C>T |
14.144 | 13.303 | 11.900 | 11.515 | 12.581 | 12.8858 |
| Wnt Signaling |
PPP3CC c.1199T>C |
12.523 | 14.479 | 9.580 | 8.556 | 10.525 | 11.5208 |
| Focal Adhesion |
BIRC2 c.1528A>G |
42.675 | 45.517 | 32.853 | 30.261 | 40.725 | 40.4425 |
| Focal Adhesion |
PPP1R12A c.254A>G |
83.939 | 83.438 | 61.009 | 55.103 | 76.460 | 70.8723 |
| Focal Adhesion |
PAK6 c.1855C>A |
8.818 | 7.144 | 5.704 | 4.970 | 6.011 | 6.6590 |
Note:
Grey color indicates the expression level in samples in which variant was present, and white color indicates the expression level of genes in samples without the presence of the analyzed variant.