Table 1. Comparison of baseline clinicopathological characteristics based on CA724 in CEA-normal CRC patients.
| Feature | Case | CA724 | χ2 | P | |
|---|---|---|---|---|---|
| Normal (242) | High (53) | ||||
| Gender | 0.026 | 0.872 | |||
| Male | 181 (61.36%) | 149 (61.6%) | 32 (60.4%) | ||
| Female | 114 (38.64%) | 93 (38.4%) | 21 (39.6%) | ||
| Age (Year) | 3.424 | 0.064 | |||
| ≤65 | 161 (54.58%) | 126 (52.1%) | 35 (66.0%) | ||
| >65 | 134 (45.42%) | 116 (47.9%) | 18 (34.0%) | ||
| pT stage | 0.594 | 0.441 | |||
| T1–2 | 98 (33.22%) | 78 (32.2%) | 20 (37.7%) | ||
| T3–4 | 197 (66.78%) | 164 (67.8%) | 33 (62.3%) | ||
| pN stage | 14.514 | 0.001 | |||
| N0 | 186 (63.05%) | 156 (64.5%) | 30 (56.6%) | ||
| N1 | 71 (24.07%) | 63 (26.0%) | 8 (15.1%) | ||
| N2 | 38 (12.88%) | 23 (9.5%) | 15 (28.3%) | ||
| Metastasis | 0.611 | 0.435 | |||
| No | 284 (96.27%) | 232 (95.9%) | 52 (98.1%) | ||
| Yes | 11 (3.73%) | 10 (4.1%) | 1 (1.9%) | ||
| Tumor location | 0.001 | 0.982 | |||
| Left side | 223 (75.6%) | 183 (75.6%) | 40 (75.5%) | ||
| Right side | 72 (24.4%) | 59 (24.4%) | 13 (24.5%) | ||
| Perineural/vascular invasion | 3.233 | 0.072 | |||
| No | 247 (83.73%) | 207 (85.5%) | 40 (75.5%) | ||
| Yes | 48 (16.27%) | 35 (14.5%) | 13 (24.5%) | ||
| Pathological type | 2.101 | 0.350 | |||
| Protrude type | 57 (19.32%) | 43 (17.8%) | 14 (26.4%) | ||
| Infiltrating type | 35 (11.86%) | 29 (12.0%) | 6 (11.3%) | ||
| Ulcerative type | 203 (68.82%) | 170 (70.2%) | 33 (62.3%) | ||
| Differentiation | 10.712 | 0.001 | |||
| Poor | 34 (11.53%) | 21 (8.7%) | 13 (24.5%) | ||
| Medium/High | 261 (88.47%) | 221 (91.3%) | 40 (75.5%) | ||
Note:
CEA, carcinoembryonic antigen; CRC, colorectal cancer; pT stage, pathological tumor stage; pN stage, pathological node stage.