Table 4. The correlation between miRNA expression and clinical parameters in GC patients (n = 74).
miRNA level | Cases (n) | Gender | Age (years) | Chemotherapy response | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Male | Female | P-value | <60 | ≥60 | P-value | Sensitive | Resistant | P-value | ||
miR-9-3p | 74 | 52 | 22 | 0.2413 | 23 | 51 | 0.5856 | 34 | 40 | <0.0001**** |
low | 37 | 24 | 13 | 9 | 28 | 24 | 13 | |||
high | 37 | 28 | 9 | 14 | 23 | 10 | 27 | |||
miR-9-5p | 74 | 52 | 22 | 0.8557 | 23 | 51 | 0.9262 | 34 | 40 | <0.0001**** |
low | 37 | 28 | 9 | 11 | 26 | 26 | 11 | |||
high | 37 | 24 | 13 | 12 | 25 | 8 | 29 | |||
miR-146a-5p | 74 | 52 | 22 | 0.7469 | 23 | 51 | 0.6510 | 34 | 40 | <0.0001**** |
low | 37 | 26 | 11 | 12 | 25 | 12 | 25 | |||
high | 37 | 26 | 11 | 11 | 26 | 22 | 15 | |||
miR-370-3p | 74 | 52 | 22 | 0.1757 | 23 | 51 | 0.8257 | 34 | 40 | 0.0611 |
low | 37 | 23 | 14 | 13 | 24 | 20 | 17 | |||
high | 37 | 29 | 8 | 10 | 27 | 14 | 23 | |||
miR-433-3p | 74 | 52 | 22 | 0.1848 | 23 | 51 | 0.3408 | 34 | 40 | <0.0001**** |
low | 37 | 24 | 13 | 9 | 28 | 24 | 13 | |||
high | 37 | 28 | 9 | 14 | 23 | 10 | 27 | |||
miR-519a-5p | 74 | 52 | 22 | 0.4414 | 23 | 51 | 0.1552 | 34 | 40 | 0.4028 |
low | 37 | 24 | 13 | 9 | 28 | 18 | 19 | |||
high | 37 | 28 | 9 | 14 | 23 | 16 | 21 | |||
miR-522-5p | 74 | 52 | 22 | 0.4414 | 23 | 51 | 0.1552 | 34 | 40 | 0.4028 |
low | 37 | 24 | 13 | 9 | 28 | 18 | 19 | |||
high | 37 | 28 | 9 | 14 | 23 | 16 | 21 |