Table 2.
Reports of failures of sugammadex in patients with myasthenia gravis
Reference | Patient demographics | Findings |
---|---|---|
Fernandes et al.[37] | 27-year-old, 110 kg woman for laparoscopic cholecystectomy | Failure of reversal of neuromuscular blockade with sugammadex (800 mg). |
Garcia et al.[38] | 35-year-old, 80 kg woman for cesarian section. | Failure of reversal of neuromuscular blockade with sugammadex (200 mg). |
Kiss et al.[39] | 25-year-old woman for thymectomy. | Persistently low train-of-four (TOF) ratio despite sugammadex (16 mg/kg). |
Sugi et al.[40] | 26-year-old woman for thymectomy. | Sugammadex (total dose 4 mg/kg) failed to restore TOF to ≥0.55. Neostigmine (30 μg/kg) resulted in successful recovery of TOF. |