Graph of baseline, 6 and 12 months follow-up short physical performance battery (SPPB) and gait speed measures testing the effect of the trial intervention, treatment, and the interaction of intervention and treatment. aShort physical performance batter (SPPB) range from 0 to 12 points.
bGait speed measured during 400 m walk test or proxy measures.
Note: Follow-up occurred at baseline visit, 6 months (6 m) and 12 months (12 m). Panels A/B: SPPB score by intervention arm and by treatment (unadjusted): Treatment × intervention (p = .298); treatment only (p = .478); intervention only (p = .002). Panels A/B: SPPB score by intervention arm and by treatment (IPTW-adjusted): Treatment × intervention (p = .443); treatment only (p = .541); intervention only (p = .012). Panels C/D: gait speed by intervention arm and by treatment (unadjusted): Treatment × intervention (p = .140); treatment only (p = .376); intervention only (p < .001). Panels C/D: gait speed by intervention arm and by treatment (unadjusted): Treatment × intervention (p = .244); treatment only (p = .179); intervention only (p < .001). All analyses conducted using analysis of covariance repeated measures.