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. 2019 May 10;75(5):849–857. doi: 10.1093/gerona/glz113

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Published by Oxford University Press on behalf of The Gerontological Society of America 2019.

This work is written by (a) US Government employee(s) and is in the public domain in the US.

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Figure 2. — Proteostatic mechanisms in the: (A) heart, (B) liver, (C) skeletal muscle, (D) subcutaneous WAT (inguinal), and (E) epididymal white adipose tissue (WAT) depots as assessed by protein synthesis (left column), DNA synthesis (middle column), and the protein/DNA synthesis ratio (right column). Rates were determined using D₂O labeling over 2 weeks. Values are presented as means ± SEM. n = 7–9 (CON), 5–6 (CR), and 9–10 (17α-E2). *p < .05 for each comparison. CR = caloric restriction; 17α-E2 = 17α-estradiol.