. 2019 Feb 14;75(5):835–842. doi: 10.1093/gerona/glz041

Table 4.

Regression of Biochemical and Demographic Factors on Cognitive Outcomes in Overweight/Obese Older Women

	Simple Reaction Time		Five-Choice Reaction Time		SOC—Problems Solved in Minimum Moves		IED Errors Adjusted		IED Total Trials Adjusted
Model 1	R ² = 0. 252 F = 1.74; p = .146		R ² = 0. 289 F = 1.74; p = .137		R ² = 0. 287 F = 1.73; p = .140		R ² = 0. 546 F = 5.16; p = .001		R ² = 0. 461 F = 3.66; p = .006
	β	p	β	p	β	p	β	p	β	p
25OHD			.252	.163
ucOC	.348	.047	.343	.045	−.272	.108	.617	<.001	.608	<.001
PTH	.238	.152	.258	.112	−.457	.007	.211	.141
Estradiol					−.247	.198	−.257	.119	−.252	.113
Aβ₄₀									.234	.117
Aβ₄₂
Model 2	R ² = 0. 422 F = 1.97; p = .079		R ² = 0. 316 F = 1.09; p = .404		R ² = 0. 332 F = 1.18; p = .349		R ² = 0. 595 F = 3.48; p = .004		R ² = 0. 603 F = 3.60; p = .004
	β	p	β	p	β	p	β	p	β	p
25OHD
ucOC	.426	.026	.356	.081	−.324	.114	.587	<.001	.567	<.001
PTH			.252	.177	−.500	.011
Estradiol							−.343	.047	−.372	.023
Aβ₄₀							.230	.132	.311	.033
Aβ₄₂
Age							.277	.116	.216	.189
Education									.242	.143
NART									.231	.095
BMI	.304	.108					−.304	.076	−.399	.015

Notes: The models include the following serum final values for 25OHD, ucOC, PTH, estradiol, Aβ₄₀ and Aβ₄₂ in Model 1, and is adjusted for demographics (age, education, NART, and BMI) for each cognitive task in the Model 2. n = 42. Values for individual variables are shown only when they reach p < .20 for inclusion in the model, and bolded when p < .09. Aβ = amyloid beta; BMI = body mass index; IED = Intra/Extra-Dimensional Set Shift; NART=National Adult Reading Test; OC = osteocalcin; PTH = parathyroid hormone; RTI = reaction time; SOC = Stockings of Cambridge; ucOC = undercarboxylated OC.