. Author manuscript; available in PMC: 2020 Apr 17.

Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2015 Jun 10;168(6):492–507. doi: 10.1002/ajmg.b.32327

Table 3.

Results of single-SNP and gene-based (rs550818 and GIT1) association analyses for brain volumes in the IMpACT-NL and BIG cohort

	IMpACT-NL cohort ^a				BIG cohort ^c
	P rs550818	β	95% CI	P GIT1 ^{b, e}	P rs550818	β	95% CI	P GIT1 ^{d, e}
Total brain volume	0.658	0.039	−0.134 - 0.211	0.563	0.897	0.511	−2.269 - 3.292	0.415
Total gray matter volume	0.622	−0.035	−0.175 - 0.105	0.497	0.970	0.069	−0.624 - 0.761	0.791
Total white matter volume	0.361	0.079	−0.084 - 0.229	0.154	0.934	0.150	−0.874 - 1.174	0.453

N=203 (101 ADHD patients). Adult ADHD patients do not differ in brain volume from healthy controls (Supplementary Table 5).

52 SNPs were considered for the gene-based analysis.

N=1,300.

43 SNPs were considered for the gene-based analysis. Total brain volume is the sum of total gray and white volume. Age, gender, magnetic field strength, and gray matter when testing for white matter and vice versa were used as covariates.

Effect sizes and 95% confidence intervals could not be estimated for the gene-based association tests.