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. 2020 Apr 17;2020(4):CD013231. doi: 10.1002/14651858.CD013231.pub2

NCT03006354.

Trial name or title Nasal high frequency oscillatory ventilation versus nasal continuous positive airway pressure in late‐preterm and term infants with transient tachypnea of the newborn: a randomized controlled trial.
Methods Open‐label RCT; sample size: 440 newborns.
Participants Late preterm and term newborn with transient tachypnea of the newborn and a Silverman Score of 4 or above on admission who require non‐invasive respiratory support.
Interventions
  • nasal high frequency oscillatory ventilation

  • nasal CPAP

Outcomes
  • Primary: Time to cessation of non‐invasive positive pressure respiratory support.

  • Secondary: Time to cessation of supplemental oxygen; Time to discharge from hospital; Pneumothorax

Starting date December 2016.
Contact information Emre Baldan, emrebaldan@e‐mail.com; Bursa Yüksek Ihtisas Teaching Hospital.
Notes Recruitment status posted on March 2017: Recruiting.

CPAP = continuous positive airway pressure
 HFNC = high‐flow nasal cannula